Yohimbine works by increasing adrenaline (epinephrine) levels and blocking alpha-2 adrenergic receptors in fat cells, which removes the natural brake on fat burning. This leads to enhanced lipolysis (fat breakdown) and makes stored fat, especially abdominal fat, more available as fuel. It also triggers a release of norepinephrine, acting as a general stimulant. By antagonizing receptors that would normally blunt fat metabolism, Yohimbine effectively amplifies the body’s ability to burn fat during exercise. Its stimulatory effect on the central nervous system also explains its benefits for libido and erectile function (via increased blood flow and nerve stimulation).